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Biographical
Information
| Date of Birth: |
May 31, 1969 |
| Place of Birth: |
Hamburg, Germany |
| Marital Status: |
married, one son (DOB: 10/10/2000), one
daughter (DOB: 27/05/02) |
Education
Medical School:
| 1988-1990: |
Hamburg Medical School |
| 1990-1991: |
Heidelberg Medical School |
| 1991-1993: |
Hamburg Medical School |
| 1993-1995: |
Lübeck Medical School |
| 1995: |
MD |
Final year
studies (3-4 months each):
| 1994: |
Neurology at the National Hospital for
Neurology and Neurosurgery, Queen Square, London, UK |
| 1994/1995: |
General Medicine at the John Radcliffe
Hospital, Oxford, UK |
Elective
periods abroad (1-2 months each):
| 1991: |
Neurology at the “Oblastnaya Bolniza”, Vitebsk
, Belarus |
| 1992: |
Pediatrics at the “S:t Görans Sjukhuset and
Karolinska Sjukhuset”,Stockholm, Sweden |
| 1993: |
General Medicine/Accident & Emergency at the
Wollongong Hospital, Wollongong, Australia |
| 1993: |
Neurology at the “Centre Hospitalier
Universitaire”, Rennes, France |
Postdoctoral
Training
Internships and Residencies:
| 1995-1997: |
Intern in Neurology, Lübeck University
Hospital, Lübeck, Germany |
| 1999-2003: |
Resident in Neurology, Lübeck University
Hospital, Lübeck, Germany |
| 2003-2004: |
Resident in Psychiatry, Lübeck University
Hospital, Lübeck, Germany |
Research
Fellowships:
| 1997-1999: |
Research Fellow in Neurogenetics,
Massachusetts General Hospital, Harvard University, Boston, USA
(Prof. X. O. Breakefield, PhD) |
| 07-11/2004: |
Research Fellow in Movement Disorders, Toronto
Western Hospital, University of Toronto, Toronto, Canada (Prof. A.
E. Lang, MD) |
| 07-10/2005: |
Clinical Fellow in Movement Disorders, Toronto
Western Hospital, University of Toronto, Toronto, Canada (Prof. A.
E. Lang, MD) |
Licensure and
Specialty Certification:
| 1995: |
National Board of Medical Examiners Licensing
examination |
| 1997: |
Schleswig-Holstein College of Physicians
General License |
| 2004: |
Specialty Certification in Neurology |
| 2005: |
College of Physicians and Surgeons of Ontario
Educational License (#83478) |
Medical thesis:
| 1990-1991: |
Elective in Molecular Genetics at the Center
for Molecular Biology, Heidelberg |
| 1991-1992: |
Medical thesis at the Center for Molecular
Neurogenetics, Hamburg |
| 1995: |
“Promotion” (“Characterization of synaptic
proteins of the rat”) |
“Habilitation”
(Assistant Professorship):
| 2001: |
Habilitation in Neurogenetics at the
University of Lübeck
(“Genetics of dystonia and dystonia-plus syndromes”) |
Awards and
Honors
| 1989-1995: |
Scholarship awarded by the German National
Scholarship Foundation |
| 1997-1999: |
International Research Fellowship awarded by
the German Research Foundation (DFG) |
| 2000: |
Hilde Ulrich's Foundation for Research in
Parkinson's Disease Award 2000 |
| 2000: |
Oppenheim Award of the German Dystonia
Foundation |
| 2001: |
Parkinson Award of the German Neurological
Society |
| 2003-2005: |
Heisenberg Fellowship awarded by the German
Research Foundation (DFG) |
| 2004: |
Career Development Award (Lichtenberg
Associate Professor of Clinical and Molecular Neurogenetics) by the
Volkswagen Foundation |
| 2007: |
Heinrich Pette Award of
the German Neurological Society (Deutsche Gesellschaft für
Neurologie) |
Academic and
University Appointments
| 1999-present: |
Principal Investigator in Neurogenetics |
| 2001-2005: |
Assistant Professor of Neurogenetics (Privatdozent) |
| since 03/05: |
Associate Professor of Neurology
(Lichtenberg Professor of Clinical and Molecular Neurogenetics) |
Academic
Activities
Reviewer for:
-
American
Journal of Human Genetics
-
American
Journal of Medical Genetics
-
Annals of
Neurology
-
Archieves of
Neurology
-
Brain
-
Cancer
Research
-
Clinical
Genetics
-
European
Journal of Human Genetics
-
European
Journal of Neurology
-
FEBS Letters
-
Human Genetics
-
Human
Molecular Genetics
-
Human Mutation
-
Journal of
Neurochemistry
-
Journal of
Neurology
-
Journal of
Neurology Neurosurgery and Psychiatry
-
Journal of the
Neurological Sciences
-
Lancet
Neurology
-
Movement
Disorders
-
Neurogenetics
-
Neurology
-
Neuroscience
Letters
Advisory
Committees:
GenNova (Epidemiology and Neurogenetics) at the European Academy, Bolzano,
Italy
Co-Chair of the Ethics Committee of the German Competence Net Parkinson’s
Disease
Meetings and
Teaching at International Conferences:
| 2000: |
Meeting Organizer and Co-Chair for the
Movement Disorders Society sponsored meeting “Genetics of Movement
Disorders – Gateways and Perspectives”, Lübeck |
| 2000: |
Appointed Faculty Member of the Movement
Disorder Society’s Annual Meeting |
| 2003/2004: |
Appointed Faculty Member of the American
Academy of Neurology’s Annual Meeting |
| 2004/2005: |
Appointed Faculty Member of the American
Academy of Neurology’s Annual Meeting (Plenary talk in 2005) |
| 2005: |
Appointed Faculty Member of the Movement
Disorder Society’s Annual Meeting (Plenary talk) |
| 2005: |
Appointed Faculty Member of the American
Neurological Association’s Annual Meeting (Plenary talk) |
| 2005 |
2005 Meeting Organizer and
Co-Chair for the Movement Disorders Society sponsored meeting
“Genetics of Movement Disorders – Gateways and Perspectives”, Lübeck |
| 2006 |
2006 Member of the
Congress Committee for the 12th Annual Meeting of the German Society
of Neurogenetics, Rostock |
| 2007 |
2007 Member of the Program
Committee for the 5th German Parkinson Congress, Ulm |
| 2008 |
2008 Member of the
Congress Scientific Program Committee for the Annual Meetings in
Chicago (2008) and Paris (2009) of the Movement Disorders Society |
| 2008 |
Director of the
Organization Committee for the 14th Annual Meeting of the German
Society of Neurogenetics, Lübeck |
Memberships:
-
German
Neurological Society (Deutsche Gesellschaft für Neurologie)
-
German
Dystonia Foundation (Deutsche Dystonie Gesellschaft)
-
German Society
of Neurogenetics (Deutsche Gesellschaft für Neurogenetik)
-
American
Academy of Neurology
-
Movement
Disorder Society
-
College of
Physicians and Surgeons of Ontario, Canada
-
Competence
Network Parkinson Germany
-
European
Subgroup of the International Restless Legs Study Group (IRLSSG)
-
Neuroprotection and Natural History in Parkinson Plus Syndromes (NNIPPS)
Genetic Section
-
Dystonia Study
Group USA
-
Parkinson
Study Group USA (GenePD Study)
Editorial Board:
-
Movement
Disorders
-
Neurology
University of
Lübeck Committees and Academic Responsibilities
-
Grant Reviewer
(2001-present)
-
Reviewer of
Medical Theses
-
Strategic
Planning Committee for the Department of Human Genetics (2003)
Peer-reviewed Grant Support
“Molecular genetic Studies of Early-onset Parkinsonism”
Principal Investigator: Christine Klein, MD
Agency: German Research Foundation (DFG)
Type: Research Grant, October, 1999 - December 2002
“Clinical and Molecular Genetic Studies of Myoclonus-Dystonia”
Principal Investigator: Christine Klein, MD
Agency: Fritz Thyssen Foundation
Type: Research Grant, July, 2000 - March 2003
“Molecular Genetic Study of Susceptibility Factors in Primary and
Secondary Dystonias and Dyskinesias”
Principal Investigator: Christine Klein, M.D.
German Dystonia Foundation
Type: Research Grant, October, 2000 - May 2003
“Evaluation of a Large Cohort of Patients with Sporadic or Familial
Parkinson's Disease for Involvement of the Parkin Gene”
Principal Investigator: Christine Klein, M.D.
Agency: Parkinson's Disease Foundation
Type: Research Grant, July, 2001 - June 2002
This study was aimed at the evaluation of a large patient cohort for
mutations in the parkin gene and at the development of a new assay for
mutation detection.
“Molecular and Epigenetic Studies of Myoclonus-Dystonia”
Principal Investigator: Christine Klein, M.D.
Agency: Fritz Thyssen Foundation
Type: Research Grant, April 2003 - March 2005
“Molecular Genetic and Protein Studies of Early-onset Parkinsonism”
Principal Investigator: Christine Klein, M.D.
Agency: German Research Foundation (DFG)
Type: Research Grant, October 2002 – September 2004
“Clinical, Genetic, and PET studies in DJ-1-associated Parkinsonism”
Principal Investigator: Christine Klein, M.D.
Agency: Parkinson’s Disease Foundation/National Parkinson Foundation
Type: Research Grant, July 2003 – June 2004
“Molecular genetic analysis of dopa-responsive dystonia and penetrance
studies”
Principal Investigator: Christine Klein, M.D.
Agency: Edith Fröhnert Foundation
Type: Research Grant, January 2005 – December 2007
“Clinical and molecular genetics of PINK1-associated parkinsonism”
Principal Investigator: Christine Klein, M.D.
Agency: German Research Foundation (DFG)
Type: Research Grant, January 2005 – June 2005
“Lichtenberg Award of the Volkswagen Foundation, Clinical and Molecular
Neurogenetics”
Principal Investigator: Christine Klein, M.D.
Agency: Volkswagen Foundation
Type: Career Development Award, March 2005 – February 2010
“Graduate School for Computing in Medicine and Life
Sciences”
Principal Investigator: Christine Klein, MD
Agency: German Research Foundation (DFG)
Type: Excellence Initiative Grant, 2007 – 2012
“Parkinson Network”
Sub Project Manager: Christine Klein, MD
Agency: National Genome Research Network/ Federal Ministry of Education and
Research
Type: Research Grant, June 2008 – May 2013
Publications
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